The need for more responsive public services has prompted governments worldwide to adjust their policies, practices, and structures accordingly. In federal countries, the division of powers and responsibilities between tiers of government adds important nuances to digitalization efforts, which often require cross-jurisdictional joint action to implement digital services. In this regard, some relevant questions remain unanswered: is federalism an obstacle or a driver of digitalization? Does digitalization lead to centralization? What strategies are being adopted to tackle the challenges of implementing digital policies in multilevel systems? In response to these pressing questions, programming is focusing on producing comparative research on the digitalization of public administration in federal countries targeted to practitioners, researchers, and students of digital government, federalism, and multilevel governance.